Margaret Douglas
Bef 1743 -
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| Elizabeth Wise 1758-1842 |
| Elizabeth Wise | |
| B: | 1758 |
| D: | 1842 |
| Mary Wise 1762-1822 |
| Mary Wise | |
| B: | 1762 |
| D: | 1822 |
| Abraham Outten | |
| M: | 2 Feb 1785 |
 | William Washington Wise -YOUNG |
| William Washington Wise | |
| D: | YOUNG |
| Margaret Douglas Pettit Wise | |
| B: | 1803 |
| Tully Robinson Wise 1797-1844 |
| Tully Robinson Wise | |
| B: | 16 Mar 1797 |
| D: | 20 Jul 1844 |
| James Henry Wise 1803- |
| James Henry Wise | |
| B: | 1803 |
| General Henry Alexander Wise 1806-1876 |
| General Henry Alexander Wise | |
| B: | 3 Dec 1806 |
| Drummondtown, Accomack County, VA | |
| D: | 12 Sep 1876 |
| Richmond, Henrico County, VA | |
| Anne Elizabeth Jennings 1808-1837 |
| Anne Elizabeth Jennings | |
| B: | 31 Dec 1808 |
| Nashville, Davidson County, TN | |
| M: | 23 Oct 1828 |
| Nashville, Davidson County, TN | |
| D: | 4 May 1837 |
| Richard Alsop Wise 1843-1900 |
| Richard Alsop Wise | |
| B: | 2 Sep 1843 |
| Philadelphia, Philadelphia County, PA | |
| D: | 21 Dec 1900 |
| Williamsburg, Williamsburg, VA | |
| Maria Dangerfield Peacy | |
| M: | Bef 1871 |
| Margaretta Ellen Wise 1844-1909 |
| Margaretta Ellen Wise | |
| B: | 25 Sep 1844 |
| Rio de Janiero, S-Pl, Brazil | |
| D: | 23 Mar 1909 |
| Richmond, Henrico County, VA | |
| William Carrington Mayo 1834-1900 |
| William Carrington Mayo | |
| B: | 8 Jan 1834 |
| M: | 29 Jan 1870 |
| D: | 12 Apr 1900 |
| Hon. John Sergeant Wise 1846-1913 |
| Hon. John Sergeant Wise | |
| B: | 27 Dec 1846 |
| Rio de Janiero, S-Pl, Brazil | |
| D: | 12 May 1913 |
| Princess Anne, Somerset County, MD | |
| Evelyn Byrd Beverly Douglas 1852-1925 |
| Evelyn Byrd Beverly Douglas | |
| B: | 1852 |
| M: | 3 Nov 1869 |
| D: | 1925 |
| Spencer Wise -IN INFANCY |
| Spencer Wise | |
| D: | IN INFANCY |
| Sarah Sergeant 1817-1850 |
| Sarah Sergeant | |
| B: | 24 Sep 1817 |
| Philadelphia, Philadelphia County, PA | |
| M: | 26 Nov 1840 |
| Philadelphia, Philadelphia County, PA | |
| D: | 14 Oct 1850 |
| Accomac County, VA | |
| Mary Elizabeth Lyons | |
| M: | 1853 |
| Tully Robinson Scarburgh Wise | |
| D: | YOUNG |
| Major John Wise 1769-1812 |
| Major John Wise | |
| B: | Between 1763-1769 |
| D: | 30 Mar 1812 |
| Sarah Corbin Cropper 1777-1813 |
| Sarah Corbin Cropper | |
| B: | 21 Mar 1777 |
| Virginia | |
| M: | Bef 1803 |
| D: | 21 Jan 1813 |
| Virginia | |
| Mary "Polly" Henry | |
| M: | Abt 1788 |
|
| Margaret Douglas Bef 1743- |
| Margaret Douglas | |
| B: | Bef 1743 |
| John Wise 1723-1769 |
| John Wise | |
| B: | 27 Jul 1723 |
| Virginia | |
| D: | Mar 1769 |
| Ayres Gillett 1731-Aft 1776 |
| Ayres Gillett | |
| B: | 1731 |
| D: | Aft 14 Sep 1776 |